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Psicothema was founded in Asturias (northern Spain) in 1989, and is published jointly by the Psychology Faculty of the University of Oviedo and the Psychological Association of the Principality of Asturias (Colegio Oficial de Psicólogos del Principado de Asturias).
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Psicothema, 2008. Vol. Vol. 20 (nº 3). 445-449




Disfunción orbitofrontal en la esclerosis múltiple: Iowa Gambling Task

Alberto García-Molina, Pablo Rodríguez Rajo, Pere Vendrell Gómez*, Carme Junqué i Plaja* y Teresa Roig-Rovira

Universidad Autónoma de Barcelona y * Universitat de Barcelona

La presencia de trastornos cognitivos en la esclerosis múltiple (EM) ha sido ampliamente estudiada, sin embargo la toma de decisiones apenas ha sido investigada. El presente estudio examina los procesos de toma de decisiones en pacientes con EM mediante la versión computerizada de la Iowa Gambling Task (IGT). Esta tarea fue aplicada a 18 pacientes con diagnóstico clínico de EM y 18 sujetos control sanos apareados por edad, sexo y nivel educativo. Los resultados muestran que las puntuaciones obtenidas en la IGT difieren significativamente entre los pacientes con EM y los sujetos control sanos: los pacientes con EM realizan menos elecciones favorables en la IGT que los controles. Se plantean posibles explicaciones a la alteración en la toma de decisiones observada en los pacientes con EM.

Orbitofrontal dysfunction in multiple sclerosis: Iowa Gambling Task. Cognitive dysfunction has been widely studied in multiple sclerosis (MS), however decision-making has been less investigated. The current study examined the decision-making processes of patients with multiple sclerosis (MS) using a computerized version of the Iowa Gambling Task (IGT). This task was applied to 18 patients with clinically diagnosed MS and 18 healthy control subjects matched for age, sex, and years of education. The results showed that IGT scores differ significantly between patients with MS and the healthy control subjects: the patients with MS made significantly less advantageous decisions than the controls in the IGT. Possible causes of impaired decision-making in multiple sclerosis are discussed.

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Impact factor 2022:  JCR WOS 2022:  FI = 3.6 (Q2);  JCI = 1.21 (Q1) / SCOPUS 2022:  SJR = 1.097;  CiteScore = 6.4 (Q1)